Monday, 10 March 2014

Demands for paternity testing have increased reflecting the instability of family relationship and infidelity issues occur more . Lets know about DNA and how does paternity testing done ?how accurate is DNA paternity testing ?

Deoxyribonucleic acid (DNA) is a molecule that encodes the genetic instructions used in the development and functioning of all known living organisms and many viruses. DNA is a nucleic acid; alongside proteins and carbohydrates, nucleic acids compose the three major macromolecules essential for all known forms of life. Most DNA molecules are double-stranded helices, consisting of two long biopolymers made of simpler units called nucleotides—each nucleotide is
composed of a nucleobase (guanine, adenine,thymine, and cytosine), recorded using the letters G, A, T, and C, as well as a backbone made of alternating sugars (deoxyribose) and phosphate groups (related to phosphoric acid), with the nucleobases (G, A, T, C) attached to the sugars. DNA is well-suited for biological information storage. The DNA backbone is resistant to cleavage, and both strands of the double-stranded structure store the same biological information. Biological information is replicated as the two strands are separated. A significant portion of DNA (more than 98% for humans) is non-coding, meaning that these sections do not serve a function of encoding proteins.
For paternity testing Any  kind of biological sample: blood, saliva, hairs, semen, amniotic liquid, biopsy, skeletal remains, nails, cigarette butt, chewing gum, envelopes, toothbrush or other organic remains present in all kind of clothes or objects. All cells of a person have the same DNA, so the accuracy and reliability of the results are the same, independent of the biologic material used.
HOW ACCURATE IS DNA PATERNITY TESTING?
DNA testing is the most accurate paternity and family relationship testing method currently available. Every person has a unique DNA fingerprint except for identical twins. We all inherit half of our DNA from our biological father and half from our biological mother. DNA testing tries to discover the 50% match between the child’s and the parent’s DNA profiles to prove or disprove the blood relationship. DNA parentage testing is considered to be 9you can take a paternity test before the child is born. Universal Genetics offers prenatal DNA paternity testing service to those who wish to find out paternity during pregnancy. An OB-GYN is involved in collecting the baby’s specimen during a period of time that presents the least risks to the fetus and the mother. The testing results are as accurate as a standard paternity test conducted after the child is born.99.9% accurate.
How do DNA samples for paternity testing become contaminated?

Swabs may become contaminated by contact with anther person’s DNA, maybe by someone who is collecting the sample. This can happen by someone inadvertently handling the tips of the swab, or dropping the swab. According to Dr. Donna Housley, the IDENTIGENE  lab director, “Sometimes the swabs are contaminated because people mix up the envelopes and put swabs from 2 different people in the same envelope, this is quite common. Also if a person has ever had a bone marrow transplant or a recent blood transfusion the profile could come back contaminated because we see two profiles from one individual when we amplify the DNA.”
When submitting DNA samples for paternity testing, avoid the original plastic packaging.

DNA Collection
Something else you want to avoid is placing the DNA collection swabs back into the plastic wrapper it originally arrived in. You want to place the samples directly into the paper envelope provided in the IDENTIGENE DNA collection kit.

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